Improving the Odds: How LIXTE Biotechnology (NASDAQ: LIXT) Is Working to Make Cancer Therapies More Effective

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  • LIXTE’s lead compound, LB-100, targets PP2A, a central regulator of cancer cell survival and treatment resistance
  • Clinical programs are designed to enhance existing immunotherapies and chemotherapies rather than replace them
  • Multiple active trials across ovarian clear cell cancer, colon cancer, and soft tissue sarcoma support a platform approach

Despite decades of progress in oncology, many cancers remain resistant to treatment, not because therapies are unavailable, but because tumor cells adapt. Immunotherapies and chemotherapies can produce meaningful responses, yet durability and consistency remain challenges, particularly in aggressive or rare cancer subtypes. Increasingly, research is shifting toward approaches that improve how well existing treatments work, rather than introducing entirely new drugs.

That strategy defines LIXTE Biotechnology Holdings Inc. (NASDAQ: LIXT), a clinical-stage pharmaceutical company focused on enhancing established cancer therapies by targeting a fundamental biological pathway involved in tumor survival and resistance. Rather than developing standalone…

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